Antimicrobial resistance and Nanoparticles as a new treatments

July 21st, 2019

Have you listened about the antimicrobial resistance?

What is the antimicrobial resistance?

 What is the superbugs?

Antimicrobial resistance (AMR) occurs when microorganism (mo) such as bacteria, viruses, fungi and parasites change in ways that render the meications used to cure the infections they cause ineffective. When the mo become resistant they are often call to as "superbugs"

The World Health Organization (WHO) data present situation of resistance in different kinds of bacteria:

•  Klebsiella pneumoniae (common intestinal bacteria). K. pneumoniae is a major cause of hospital-acquired infections such as pneumonia, bloodstream infections, etc.
• E. Coli, to one of the most widely used medicines for the treatment of urinary tract infections (fluoroquinolone antibiotics) is very widespread
• And others bacteria for example, gonorrhoea, Staphylylococcys aureus (a common cause of severe infections in health and community)

The WHO in the last report named diseases that the most AMR:

• Tuberculosis
• Malaria 
• HIV (human immunodeficiency virus )
• Influenza

WHO’s global surveillance report of 2014 on antibiotic resistance states that at least50% or more of WHO regions including Africa (77%), West Pacific Region (72%), East Mediterranean region (50%), South East Asia (81%) have developed resistance towards various microbes 

Nanomaterials

"The nanomaterials is proven to have potential antimicrobial properties as they efficiently eradicate disease causing pathogens without any side effects due their unique physico-chemical properties" said S.D. Lakshmi Ph. of Department of Medical Electronics, BMS College of Engineering  in India.

The research and developments of new nanomaterials for treatments of diseases are hope to overcome AMR. There are many metal and non-metal nanoparticles which possess biocidal properties such as copper, gold, silver, silica, zinc oxide, carbon-based nanomaterials etc. One of them are Gold nanoparticles used in treatment of cancer. 

In other blog I'm going to talk about my research  "Synthesis and characterization of hollow gold nanoparticles loaded with doxorubicin for the treatment of ovarian cancer"

This is a beginin of a larger  investigation of new nanomaterials as a antimicrobial agents and new  treatments diseases. 

I'll talk more in the new post, every sunday upload a new information of these topic.

This is the end of the first part of investigation see you the next sunday 

Bibliography:

https://www.sciencedirect.com/science/article/pii/S2352507X18300386  

https://doi.org/10.1016/j.nanoso.2018.08.001 

https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance 

Este blog utiliza información publicada en diferentes artículos científicos de libre acceso, comentando y dando a conocer dichas investigaciones, en ningún momento el autor de este blog hace mención a él mismo como el investigador o reclama la misma. Este blog es hecho para recreación y divulgación científica de libre acceso.

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